The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins.
They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell.
IL-17RC (interleukin-17 receptor C) is a 791 amino acid single-pass type I transmembrane protein that may function as a receptor for IL-17.
Existing as multiple alternativelyspliced isoforms, IL-17RC is expressed in heart, brain, intestine, liver, kidney, lung, muscle, placenta and prostate, and is encoded by a gene which maps to human chromosome 3.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of IL-17RC. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 720-770 of Human IL-17RC.
