84-2350-45 ［取扱停止］IKBK-epsilon (I kappa B Kinase epsilon, I-kappa-B Kinase epsilon, IkBKE, IKBKE Protein, IKK E, IKK i, IKK Related Kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKE, IKKepsilon, IKKI, Inducible I kappa B Kinase, Inducible I kappa-B Kinase, inducible IkappaB Kinase, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase epsilon, Inhibitor of Nuclea ... 223516
84-2350-45 ［取扱停止］IKBK-epsilon (I kappa B Kinase epsilon, I-kappa-B Kinase epsilon, IkBKE, IKBKE Protein, IKK E, IKK i, IKK Related Kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKE, IKKepsilon, IKKI, Inducible I kappa B Kinase, Inducible I kappa-B Kinase, inducible IkappaB Kinase, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase epsilon, Inhibitor of Nuclea ... 223516
The functional IKK complex contains three subunits, IKKalpha, IKKbeta and IKKγ (also designated NEMO), and each appear to make essential contributions to IκB phosphorylation.
IKK-i is a serine/threonine kinase that shares homology with IKKalpha and IKKbeta.
IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFalpha, IL-1 and IL-6.
Overexpression of IKK-i was shown to result in phosphorylation of IκBalpha on Ser32 and Ser36, and in NFκB activation, suggesting that IKK-i may act as an IκB kinase in the immune system.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of IKBKE. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant full length Human IKBKE.
Shelf Life：1year
Swiss Prot Number：Q14164
EU Commodity Code：30021010
商品名：IKBK-epsilon (I kappa B Kinase epsilon, I-kappa-B Kinase epsilon, IkBKE, IKBKE Protein, IKK E, IKK i, IKK Related Kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKE, IKKepsilon, IKKI, Inducible I kappa B Kinase, Inducible I kappa-B Kinase, inducible IkappaB Kinase, Inhibitor of kappa Light Polypeptide Gene Enhancer in B Cells Kinase epsilon, Inhibitor of Nuclear Factor kappa B Kinase Subunit epsilon, Inhibitor of Nuclear Factor kappa-B Kinase Subunit epsilon, KIAA0151, MGC125294, MGC125295, MGC125297) 50ul
