Transcription regulator of hematopoietic cell differentiation.
Binds gamma-satellite DNA.
Binds with higher affinity to gamma satellite A.
Plays a role in the development of lymphocytes, B- and T-cells.
Binds and activates the enhancer (delta-A element) of the CD3-delta gene.
Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation.
Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes.
Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes.
Increases normal apoptosis in adult erythroid cells.
Confers early temporal competence to retinal progenitor cells (RPCs).
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of Ikaros. Species Crossreactivity: Human, mouse, rat
