IgG is a monomeric immunoglobulin composed of two heavy chains and two light chains.
There are 4 subclasses of the IgG: IgG-1, IgG-2, IgG-3 and IgG-4.
Each molecule has two antigen binding sites.
IgG is the most abundant immunoglobulin as well as the only isotype that can pass through the placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed.
IgG can bind to several different kinds of pathogens, for example viruses, bacteria, and fungi, and it protects the body against them by complement activation (the classic pathway), opsonization for phagocytosis, and neutralization of their toxins.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of IGHG1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 211-260 of Human IGHG1.
