84-2347-55　［取扱停止］HoxA11/D11 (Homeobox Protein Hox-A11, Homeobox Protein Hox-1I, HOXA11, HOX1I, Homeobox Protein Hox-D11, Homeobox Protein Hox-4F, HOXD11, HOX4F) 100ul　223363

特徴

• The homeobox gene HOXA11, also designated homeobox 1I (HOX1I), belongs to the AbdB homeobox family.
• HoxA11 is necessary for fertility in females as it is a regulator of the cyclic development of the adult endometrium and embryonic uterine development.
• The expression of HoxA11 increases drastically during the midluteal stage of the menstrual cycle, which is necessary for implantation of the blastocyst.
• HoxD11 (homeobox D11), also known as HOX4 or HOX4F, is a 338 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family.
• Localized to the nucleus, HoxD11 functions as a sequencespecific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis.
• Defects in the gene encoding HoxD11 are associated with severe limb and genital abnormalities, suggesting that HoxD11 plays an important role in forelimb morphogenesis.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.