84-2346-48　［取扱停止］HLA-G (HLA class I histocompatibility Antigen, alpha Chain G, HLA G Antigen, MHC class I Antigen G, HLA-G, HLA-6.0, HLAG) 100ul　223309

特徴

• Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes.
• MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and a non-covalently associated protein, b-2-microglobulin.
• Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules.
• Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove.
• MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain.
• Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules.
• MHC class II molecules bind 13-18 amino acid antigenic peptides.
• Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.