The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins.
CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns.
Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases.
This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of HAVCR2. Species Crossreactivity: Human
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant full length Human HAVCR2.
Shelf Life:1year
Swiss Prot Number:Q8TDQ0
EU Commodity Code:30021010
商品名:HAVCR2 (FLJ14428, HAVcr-2, Havcr2, HAVR2_HUMAN, Hepatitis A virus Cellular Receptor 2, Kidney injury Molecule 3, KIM 3, KIM3, T Cell immunoglobulin and mucin Domain Containing 3, T Cell immunoglobulin mucin 3, T-Cell immunoglobulin and mucin Domain-Containing Protein 3, T-Cell immunoglobulin mucin Family Member 3, T-Cell immunoglobulin mucin Receptor 3, T-Cell Membrane Protein 3, Tim 3, TIM-3, TIM3, TIMD-3, TIMD3,) 50ul