84-2343-21　［取扱停止］GYS (Glycogen [starch] Synthase, muscle, GYS1, GYS, Glycogen Synthase) 100ul　223132

特徴

• Glycogen (starch) synthase belongs to the mammalian/fungal glycogen synthase family of proteins.
• Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway.
• Glycogen synthase transfers the glycosyl residue from UDP-glucose to the nonreducing end of alpha-1,4-glucan.
• The 81kDa liver glycogen synthase protein is truncated by 34 amino acids compared to the muscle form.
• However, these enzymes differ significantly in their amino- and carboxyl-terminal regions.
• Muscle glycogen synthase serves to fuel muscular activity only and is regulated by muscle contraction and by catecholamines.
• Liver glycogen synthase mediates blood glucose homeostasis in response to nutritional cues.
• Defects in the gene encoding liver glycogen synthase results in glycogen storage disease type 0 (GSD0), a rare form of fasting ketotic hypoglycemia.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.