C3orf39 (chromosome 3 open reading frame 39), also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family.
C3orf39 is encoded by a gene that maps to human chromosome 3p25.1.
Chromosome 3 is made up of ~214 million bases encoding over 1,100 genes.
Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3.
Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells.
Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.
Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of GTDC2. Species Crossreactivity: Human
