G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways.
G protein-coupled receptors translate extracellular signals into intracellular signals (G protein-activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters.
GPR15 (G protein-coupled receptor 15) is a 360 amino acid multi-pass membrane protein belonging to the G protein-coupled receptor 1 family.
GPR15 is thought to function as a chemokine receptor and is encoded by a gene that maps to murine chromosome 16 C1.2.
Applications:Suitable for use in Immunofluorescence, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity:Recognizes endogenous levels of GPR15. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:IF WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to the 248-293 of Human GPR15.