84-2340-87　［取扱停止］GPC3 (DGSX, Glypican Proteoglycan 3, Glypican-3 [Precursor], Gpc3, GPC3_HUMAN, GTR2 2, GTR2-2, Heparan sulphate Proteoglycan, Intestinal Protein OCI 5, Intestinal Protein OCI-5, MXR7, OCI 5, OCI-5, OCI5, SDYS, Secreted glypican-3, SGB, SGBS, SGBS1,) 50ul　223012

特徴

• Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains.
• Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage.
• These proteins may play a role in the control of cell division and growth regulation.
• The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types.
• Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome.
• Alternative splicing results in multiple transcript variants.
• Applications:Suitable for use in Western Blot and Immunofluorescence .
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1:500-1:2000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.