84-2340-64　［取扱停止］GnRH I (Progonadoliberin-1, Progonadoliberin I, Gonadoliberin-1, Gonadoliberin I, Gonadorelin, Gonadotropin-releasing Hormone I, GnRH-I, Luliberin I, Luteinizing Hormone-releasing Hormone I, LH-RH I, GnRH-Associated peptide 1, GnRH-Associated peptide I, GNRH1, GNRH, GRH, LHRH) 100ul　223000

特徴

• GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the median eminence.
• GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary.
• In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain.
• GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells.
• Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions.
• GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.