Glypican-5 is also known as GPC5 and is a 572 amino acid protein.
Glypican-5 is primarily expressed in adult brain tissue (where it is localized to neurons), but is also detected in fetal brain, lung and liver.
Glypican-5 is a member of the glypican-related integral membrane proteoglycan family (GRIPS), which is characterized as having a core protein that is able to use glycosyl phosphatidylinositol to attach to the cytoplasmic membrane.
Upregulation of glypican-5 has been found in active multiple sclerosis plaques, suggesting that glypican-5 may be involved in pathogenesis of multiple sclerosis.
Upregulation of glypican-5 has also been recognized as having a strong correlation with lymphomas, as well as other tumors.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of Glypican-5. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 140-185 of Human Glypican-5.
