84-2340-21　［取扱停止］Glut 3 (Glucose Transporter GLUT3, Glucose Transporter Type 3. brain, GLUT-3, GLUT3, 6515, SLC2A3, 138170, P11169, GLUT3) 50ul　222979

特徴

• Glucose is the major source of our energy and there are numerous isoforms of the glucose transporter in mammals, including Glut1, Glut2, Glut3, Glut4, Glut5, Glut6, Glut7, Glut8 and Glut9.
• The Glut5 gene located on the short arm of human chromosome 1 encodes a 501-amino acid facilitative glucose transporter.
• Glut5 mRNA is highly expressed in small intestine and to a lesser extent in kidney, skeletal muscle and adipose tissue.
• Glut5 plays a critical role in fructose absorption in the small intestine and its expression is highly induced when exposed to a fructose-enriched diet.
• Glut5 transporter expressed in human skeletal muscle is specifically localized to the plasma membrane, where it participates in regulating hexose transfer across the sarcolemma.
• Glut8, a novel glucose transporter-like protein, exhibits significant sequence similarity with the other members of sugar transporter family.
• Glut8 comprises 12 putative membrane-spanning helices and several conserved motifs, which are important for transport activity.
• In human tissues, Glut8 is predominantly expressed in testis and, to a lesser extent, in most other tissues including skeletal muscle, heart, small intestine and brain.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.