Small synthetic molecules called growth-hormone secretagogues (GHSs) act through GSH-R to stimulate the release of GH from the pituitary.
Ghrelin is an endogenous levels of ligand for the growth hormone secretagogue receptor (GHS-R).
Ghrelin and GHRH are involved in the regulation of GH release from the pituitary.
GHRH exerts its action through high-affinity GHRH receptors (GHRH-R) present in the anterior pituitary.
The acylated peptide of ghrelin specifically releases GH both in vivo and in vitro and is found in stomach tissue.
GH plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species.
The gene encoding ghrelin maps to human chromosome 3p26-p25.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of Ghrelin. Species Crossreactivity: Human, mouse, rat
