Myostatin (GDF8) is expressed uniquely in human skeletal muscle as a 12kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma.
Myostatin is a member of the transforming growth factor ß superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass.
Studies have shown that myostatin could play an important role in cardiac development and physiology.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of GDF-8. Species Crossreactivity: Human, mouse
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to amino acids 11-60 of Human GDF-8.