Though originally implicated in the regulation of feeding behavior, the neuropeptide Galanin is now known to be is involved in several physiological functions, including reproduction, and that it also inhibits various aspects of neurotransmission and memory.
Galanin influences gonadotrophin-releasing hormone secretion in the hypothalamo-pituitary axis.
Galanin is localized in brain pathways involved in both cognition and affect, and may inhibit learning and memory by inhibiting neurotransmitter release and neuronal firing rate.
Galanin is upregulated in primary afferent and sympathetic neurones and may be involved in the development of sympathetic perineuronal baskets (“rings”) following nerve injury).
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human GAL.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to full length human GAL.
