Glucose-6-phosphate 1-dehydrogenase (G6PD) plays an important role in the pentose phosphate pathway.
It is a member of the glucose-6-phosphate dehydrogenase family of proteins.
G6PD is an ubiquitous enzyme that produces pentose sugars for nucleic acid synthesis, but is also involved in carbohydrate degradation, as it is one of the main producers of NADPH reducing power.
G6PD has NADP as a co-factor and structural element.
It can be found as a homodimer or homotetramer, and is primarily detected in lymphoblasts, granulocytes and sperm.
Defects in G6PD can cause chronic non-spherocytic hemolytic anemia (CNSHA), especially in areas in which malaria is an epidemic.
Individuals with a high level of G6PD-deficiency are at higher risk of acute hemolytic attacks.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of G6PD. Species Crossreactivity: Human, mouse, rat
