All human blood, with rare exception, carries the red cell H antigen.
The H blood group locus determines expression of the H antigen in the erythroid lineage, whereas a unique locus (the SE (secretion) locus) controls H expression in a variety of secretory epithelia and in saliva.
Individuals of the Bombay phenotype lack H antigen, whereas individuals of the para-Bombay phenotype synthesize H determinants (essential precursors to A and B antigens) in their secretory epithelia but not in the erythroid lineage.
The H and SE loci, which may have arisen by gene duplication from a common ancestral gene, are known as FUT1 and FUT2, respectively, and are tightly linked on chromosome 19q13.3 .
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of FUT2. Species Crossreactivity: Human
