The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers.
FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of ~110 amino acids.
FOX transcription factors play roles in determining cell fate during early development.
FOXR1 (forkhead box protein R1), also known as FOXN5 (forkhead box protein N5) or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain.
Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR1 may be involved the development of certain invasive carcinomas.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of FoxR1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 232-286 of Human FoxR1.
