Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromodulin, and Lumican mediate extracellular matrix organization and are binding partners of TGFbeta.
Fibromodulin is a collagen-binding Keratan sulphate proteoglycan that influences adhesion processes of connective tissue, and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness.
The core proteins of SLRPs consist of a central region of leucine-rich repeats flanked by disulfide-linkages of the terminal domains.
Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon, and ligament.
The human Fibromodulin gene maps to chromosome 1q32 and encodes a 376 amino acid protein.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of FMOD. Species Crossreactivity: Human, mouse, rat
