FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase.
A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA(Phe).
This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA(Phe).
FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of FARSLB. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human FARSLB.
