84-2333-18　［取扱停止］FAM82A2 (Cerebral Protein 10, FAM82C, FAM82C, formerly, Family with Sequence similarity 82 Member C, Family with Sequence similarity 82 Member C, formerly, Family with Sequence similarity 82, Member A2, FLJ10579, hRMD 3, Microtubule Associated Protein, Protein FAM82A2, Protein FAM82C, Protein Tyrosine Phosphatase interacting Protein 51, PTPIP51, Regulator of micro ...　222618

特徴

• PTPIP51 (protein tyrosine phosphatase-interacting protein 51), also known as FAM82A2 (family with sequence similarity 82, member A2), FAM82C, RMD3 (regulator of microtubule dynamics protein 3) or cerebral protein 10, is a 470 amino acid protein belonging to the FAM82/RMD family that may play a role in differentiation and apoptosis of keratinocytes.
• In addition to exhibiting nuclear and mitochondrial membrane localization, PTPIP51 also localizes to cytoplasm during interphase and spindle microtubules and spindle poles during mitosis.
• While widely expressed, PTPIP51 is found at high levels in epidermis, seminiferous epithelium and fast twitch fibers of skeletal muscle.
• PTPIP51 has also been found in hippocampal neurons, axons of the peripheral nervous system and ganglion cells of the autonomic nervous system.
• PTPIP51 may function as a cellular signaling partner in angiogenesis and vascular remodeling, and overexpression of PTPIP51 is known to induce apoptosis.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.