Members of the FAM3 family were identified based on structural, but not sequence, homology to short chain cytokines including IL-2, IL-4 and GM-CSF.
FAM3 proteins are four helix bundle cytokines with four conserved cysteines in all members (FAM3A-D).
FAM3B (also known as PANDER, for pancreatic derived factor) is highly expressed in alpha and beta cells of the pancreas and is being investigated as a potential contributor to beta cell death and development of type I diabetes.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of FAM3D. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 168-220 of Human FAM3D.
