Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism.
FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues.
The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs.
FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP).
MDGI is highly expressed in the myocardium, skeletal and smooth muscle fibers, lipid and/or steroid synthesizing cells and terminally differentiated epithelia of the respiratory, intestinal and urogenital tracts.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of FABP3. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant full length Human FABP3.
Shelf Life：1year
Swiss Prot Number：P05413
EU Commodity Code：30021010
商品名：FABP3 (Cardiac Fatty Acid Binding Protein, FABP 11, FABP 3, FABP11, FABP3, FABPH_HUMAN, Fatty acid Binding Protein 11, Fatty acid Binding Protein 3, Fatty acid Binding Protein 3 muscle and heart, Fatty acid Binding Protein 3 muscle and heart mammary derived Growth Inhibitor, Fatty acid Binding Protein 3 muscle, Fatty acid Binding Protein 3, muscle and heart (mammary derived Growth Inhibitor), Fatty acid Binding Protein 3, muscle, Fatty acid Binding Protein heart, Fatty acid Binding Protein, heart, Fatty acid Binding Protein, muscle and heart, Fatty acid Binding Protein, skeletal muscle, Fatty acid-Binding Protein 3, Fatty acid-Binding Protein, H FABP, H-FABP, heart, Heart Type fatty acid Binding Protein, Heart-Type fatty acid-Binding Protein, M FABP, M-FABP, Mammary derived Growth Inhibitor, Mammary-derived Growth Inhibitor, MDGI, Muscle fatty acid Binding Protein, Muscle fatty acid-Binding Protein, Mylein Protein P2 Homolog, O FABP, OTTHUMP00000003898, P2 adopocyte Protein) 100ul
