84-2332-33　［取扱停止］Ezrin (Cytovillin, Villin-2, Villin2, p81, EZR, VIL2) 100ul　222576

特徴

• Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane.
• The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins.
• Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor.
• Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78.
• Moesin and Radixin share over 70% homology with Ezrin and are coexpressed within various cell types.
• Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.