84-2330-72　［取扱停止］ER81 (ETV1, ER81, ETS Translocation Variant 1, Ets-Related Protein 81) 50ul　222496

特徴

• Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element.
• All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core.
• ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'.
• ER81 is highly expressed in brain, testis, lung and heart.
• ER81 is also moderately expressed in spleen, pancreas, colon and small intestine.
• During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis.
• ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.