To date, at least 14 members of the Eph receptor family and a family of 8 ligands have been identified.
Ligands of Eph family receptors are structurally related membrane bound proteins that can be subdivided into two major subclasses: ephrin A and ephrin B.
Ligands in the ephrin A subclass, including the prototype family member ephrin A1 (B61), are membrane associated through glycosylphosphatidyl inositollinkages; whereas ephrin B subclass consists of ligands with transmembrane domains.
The general role of the Eph family is in mediating repulsive cell to cell interaction, as suggested by studies of axonal guidance and neural crest cell migration.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of Ephrin-A4. Species Crossreactivity: Human, mouse, rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to amino acids 50-100 of Human Ephrin-A4.