Autotaxin (ATX), also designated ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2), is a membrane-bound glycoprotein that cleaves diester bonds for a broad range of substrates.
Originally isolated from the human melanoma cell line (A2058), Autotaxin is predominantly expressed in brain, placenta, ovary and small intestine.
Autotaxin has significant homology to the cell membrane differentiation antigen PC-1, and is a stimulator of tumor cell motility.
It also functions as a catalyst by hydrollytically removing 5’-nucleotides from the 3’-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of ENPP2. Species Crossreactivity: Human, mouse, rat
