84-2328-50　［取扱停止］eIF6 (Eukaryotic Translation Initiation Factor 6, eIF-6, B(2)GCN Homolog, B4 integrin Interactor, CAB, p27(BBP), EIF6, EIF3A, ITGB4BP, OK/SW-cl.27) 50ul　222386

特徴

• Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.
• May behave as a stimulatory translation initiation factor downstream insulin/growth factors.
• Is also involved in ribosome biogenesis.
• Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
• Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.