84-2327-01　［取扱停止］EEA1 (Early endosome Antigen 1, Endosome-Associated Protein p162, Zinc Finger FYVE Domain-Containing Protein 2, ZFYVE2) 50ul　222309

特徴

• Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport.
• EEA1 (early endosome antigen 1) is a peripheral membrane protein that colocalizes with the transferrin receptor and Rab5 on early endosomes.
• EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes.
• EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1.
• Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.