Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases.
DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38.
The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of DUSP6. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 43-98 of Human DUSP6.
Shelf Life：1year
Swiss Prot Number：Q16828
EU Commodity Code：30021010
商品名：DUSP6 (Dual Specificity Phosphatase 6, Dual Specificity Phosphatase 6 Isoform a, Dual Specificity Protein Phosphatase 6, Dual Specificity Protein Phosphatase PYST1, DUS6, DUSP 6, DUSP 6a, Dusp6, DUSP6a, MAP Kinase Phosphatase 3, Mitogen Activated Protein Kinase Phosphatase 3, Mitogen-Activated Protein Kinase Phosphatase 3, MKP 3, MKP-3, MKP3, PYST 1, PYST1, Serine/threonine specific Protein Phosphatase) 50ul
