PECI (peroxisomal D3,D2-enoyl-CoA isomerase), also known as DRS1, ACBD2 or HCA88, is a 359 amino acid protein that localizes to the peroxisomal matrix and contains one ACB (acyl-CoA-binding) domain.
Expressed abundantly in liver, heart and skeletal muscle, PECI functions to catalyze the isomerization of both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species, playing an important role in the beta-oxidation of unsaturated fatty acids.
The gene encoding PECI maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of DRS-1. Species Crossreactivity: Human
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to amino acids 81-130 of Human DRS-1.
Shelf Life:1year
Swiss Prot Number:O75521
EU Commodity Code:30021010
商品名:DRS-1 (ACBD2, acyl Coenzyme A Binding Domain Containing 2, D3 D2 enoyl CoA Isomerase, DBI Related Protein 1, Delta(3) delta(2) enoyl CoA Isomerase, Diazepam-Binding Inhibitor-Related Protein 1, Dodecenoyl CoA Isomerase, DRS 1, DRS1, HCA88, Hepatocellular Carcinoma Associated Antigen 88, Peroxisomal 3, 2-trans-enoyl-CoA Isomerase, Peroxisomal D3 D2 enoyl CoA Isomerase, Renal Carcinoma Antigen NY REN 1) 100ul