The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding.
These transmembrane proteins include the adrenergic, serotonin and dopamine receptors.
The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds.
ß-adrenergic receptor binds to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor binds to adrenaline inhibits adenylyl cyclase.
The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase while D2 receptors inhibit adenylyl cyclase activity.
Five different subtypes of dopamine receptor have been described to date.
D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of DRD3. Species Crossreactivity: Human
