Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement.
Cytoplasmic or axonemal dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors.
Dynein complexes transport cellular cargos toward the central region of the cell.
Containing one to three non-identical heavy chains, axonemal dynein motors cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia movement and cell propulsion.
DNAL1 (dynein light chain 1, axonemal), also known as MGC12435 or C14orf168, is a 190 amino acid member of the dynein light chain LC1-type protein family.
Containing four leucine-rich repeats, DNAL1 interacts directly with DNAH5.
DNAL1 is expressed in testis and other tissues carrying motile cilia.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of DNAL1. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to amino acids 128-184 of Human DNAL1.
