84-2324-67　［取扱停止］DNA Polymerase delta 3 (DNA Polymerase delta Subunit 3, DNA Polymerase delta Subunit p66, POLD3, KIAA0039, DNA pol delta3, DNA poldelta3, DNApoldelta3, DNA pol delta p66, DNA poldelta p66) 100ul　222188

特徴

• DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases.
• In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches.
• These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and ε.
• DNA pol delta and DNA pol ε are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA.
• DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.
• Applications:Suitable for use in Western Blot, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunocytochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.