84-2324-10 [取扱停止]Di-Ras1 (Di Ras1, DIRAS Family GTP Binding RAS like 1, Distinct subgroup of the Ras Family Member 1, FLJ42681, GBTS1, GTP Binding Protein Di Ras1, Ras Related Inhibitor of Cell Growth, RIG, Rig Protein) 50ul 222159
84-2324-10 [取扱停止]Di-Ras1 (Di Ras1, DIRAS Family GTP Binding RAS like 1, Distinct subgroup of the Ras Family Member 1, FLJ42681, GBTS1, GTP Binding Protein Di Ras1, Ras Related Inhibitor of Cell Growth, RIG, Rig Protein) 50ul 222159
Members of the Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion.
The counter-conversion of the active GTP-bound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange.
DIRAS1 (DIRAS family, GTP-binding Ras-like 1), also known as distinct subgroup of the Ras family member 1, RIG (Ras-related inhibitor of cell growth), small GTP-binding tumor suppressor 1 or GBTS1, is a 198 amino acid cell membrane protein expressed at high levels in brain and heart.
DIRAS1 displays low GTPase activity and is encoded by a gene that maps to human chromosome 19p13.3.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity:Recognizes endogenous levels of Di-Ras1. Species Crossreactivity: Human
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to amino acids 151-200 of Human Di-Ras1.