DHRS9 (dehydrogenase/reductase (SDR family) member 9), also known as RDHL, RDH15, RDHTBE, SDR9C4 or RETSDR8, is a 319 amino acid protein that localizes to the membrane of both the microsome and the endoplasmic reticulum and belongs to the short-chain dehydrogenase/reductase family.
Expressed at high levels in trachea and epidermis and present at lower levels in brain, colon, heart, lung, testis, placenta and skeletal muscle, DHRS9 functions as a homotetramer that converts both 3-alpha-tetrahydroprogesterone (allopregnanolone) and 3-alpha-androstanediol to dihydroxyprogesterone and is thought to play a role in retinoic acid biosynthesis.
Multiple isoforms of DHRS9 exist due to alternative splicing events.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of DHRS9. Species Crossreactivity: Human
