Dynactin, a multisubunit complex, is a cytoplasmic dynein-interacting protein that functions as the ‘receptor’ for the dynein microtubule motor.
Dynactin-dynein binding may be required for most, if not all, cytoplasmic dynein driven activities and is thought to contribute to dynein’s functional diversity.
Dynactin, enriched in neurons, also binds to microtubules and has been shown to function in diverse processes, including organelle transport, formation of the mitotic spindle and cytokinesis.
Dynactin subunits include p22, p50, p62, p150, (also designated Glued), and Arp1.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of DCTN1. Species Crossreactivity: Human, mouse, rat
