84-2322-28　［取扱停止］Cytokeratin 20 (Keratin, Type I Cytoskeletal 20, Cytokeratin-20, Short name=CK-20, Keratin-20, Short name=K20, Protein IT, KRT20, CK 20, CK20, Keratin 20) 50ul　222066

特徴

• Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epi-thelial cells.
• The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments.
• Cytokeratins are useful markers of tissue differentiation, and in addition, they aid in the characterization of malignant tumors.
• Cytokeratin 20 is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract, and Cytokeratin 20 is a useful marker of pancreatic and colorectal cancer.
• Cytokeratin 20 is also helpful in distinguishing different types of highly related carcinomas, such as renal oncocytomas from renal cell carcinomas.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.