84-2319-57　［取扱停止］CTCFL (BORIS like Protein, Brother of the Regulator of Imprinted sites, Cancer/Testis Antigen 27, CCCTC Binding Factor (zinc Finger Protein) like, CCCTC-Binding Factor, CT27, CTCF paralog, CTCF T, CTCF-like Protein, Ctcfl, CTCFL_HUMAN, dJ579F20.2, HMG 1L1, HMGB1L1, MGC163358, MGC169105, MGC169106, Putative High Mobility Group Protein 1 like 1, Putative High Mobili ...　221929

特徴

• Brother of the regulator of imprinted sites (BORIS) is a mammalian transcription factor that is paralogous to the CCCTC-binding factor (CTCF), an ubiquitous 11 zinc finger (ZF) protein that organizes epigenetically controlled chromatin insulators that regulate imprinted genes in soma.
• BORIS is a 663 amino acid DNA binding protein.
• It is expressed at high levels in the testis and in low levels in the prostate in a mutually exclusive pattern that correlates with the re-setting of methylation marks during male germ cell differentiation.
• Abnormal expression of BORIS is linked to many types of cancer including breast, pro-state, ovary, gastric, liver, endometrial, glia, colon and esophagus.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.