CT47 (cancer/testis antigen family 47) is a 288 amino acid protein that is strongly expressed in testis and lowly expressed in placenta and in brain.
The gene encoding CT47 is located on human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes.
The combination of an X and y chromosome lead to normal male development while two copies of X lead to normal female development.
There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited.
More than one copy of the X chromosome with a y chromosome causes Klinefelter's syndrome.
A single copy of X alone leads to Turner's syndrome.
More than 2 copies of the X chromosome, in the absence of a y chromosome, is known as Triple X syndrome.
Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of CT47. Species Crossreactivity: Human, mouse, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to residues in Human CT47.
