Citrate synthase (CS) is a 466 amino acid mitochondrial matrix protein that functions as the first and rate-limiting enzyme of the tricarboxylic acid cycle.
Essential in mitochondrial respiration and involved in the conversion of glucose to lipid, citrate synthase is found the great majority of cells that are capable of oxidative metabolism.
The gene encoding citrate synthase maps to human chromosome 12q13.2, which is transcribed into two alternatively spliced variants designated CSa and CSb.
Human chromosome 12 encodes over 1,100 genes, comprises ~4.5% of the human genome and is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CS. Species Crossreactivity: Human, mouse, rat
