Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens.
Crystallins are divided into alpha, beta, and y families, and the beta and y-crystallins also comprise a superfamily.
Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions.
y-crystallins are structural proteins in the lens, and they exists as monomers which typically lack connecting peptides and terminal extensions.
The y-crystallins include seven closely related proteins, namely yA-, yB-, yC-, yD-, yE-, yF-, and yG-crystallin, as well as the yN and yS-crystallin proteins.
The y-crystallins are differentially regulated after early development, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CRYGD. Species Crossreactivity: Human, mouse, rat
