Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens.
Crystallins are divided into a, b, and g families, and the b- and g-crystallins also comprise a superfamily.
Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions.
b-crystallins constitute the major lens structural proteins.
They associate into dimers, tetramers, and higher order aggregates.
The b-crystallin subfamily is composed of several gene products, including bA1-, bA2-, bA3-, bA4-, bB1-, bB2- and bB3-crystallin.
The bA1- and bA3-crystallin proteins are encoded by a single mRNA.
They differ by only 17 amino acids, and bA1-crystallin is generated by use of an alternate translation initiation site.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CRYBB1. Species Crossreactivity: Human, mouse, rat
