84-2316-60　［取扱停止］CNGA2 (Cyclic Nucleotide-Gated olfactory Channel, Cyclic Nucleotide-Gated cation Channel 2, Cyclic Nucleotide-Gated Channel alpha-2, CNG Channel alpha-2, CNG-2, CNG2, CNGA2, CNCA, CNCA1, CNCG2) 50ul　221778

特徴

• Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits.
• The alpha subunits consist of CNG1-3 and form functional cation channels by themselves.
• The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels.
• CNG channels are essential components of olfactory and visual transduction.
• In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP.
• In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP.
• CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel.
• CNG channels have been implicated in other areas.
• Applications:Suitable for use in Immunofluorescence, Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.