CFDP1 (Craniofacial development protein 1), also known as Bucentaur and CP27, is a 299 amino acid protein that is involved in embryogenesis and normal cell function.
When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with antibodies against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration.
CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart.
The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A.
There are two isoforms of CFDP1 that are produced as a result of alternative splicing events.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of CFDP1. Species Crossreactivity: Human, mouse, rat
