84-2313-06 [取扱停止]Cdc40 (Pre-mRNA-processing Factor 17, Cell Division Cycle 40 Homolog, EH-Binding Protein 3, Ehb3, PRP17 Homolog, hPRP17, CDC40, EHB3, PRP17, PRPF17) 100ul 221594
特徴
- Cdc40, also known as pre-mRNA-processing factor 17 (PRPF17) or EH-binding protein 3 (EHB3), is a 579 amino acid nuclear protein.
- Cdc40 is essential for the catalytic step II of the pre-mRNA splicing process, in which Cdc40 associates with the spliceosome C complex.
- Cdc40 contains seven WD repeats, which are important in protein-protein interactions.
- Cdc40 has sequence similarity to the yeast protein Prp17, which is involved in pre-mRNA splicing and cell cycle progression.
- The sequence similarity between the mammalian Cdc40 and the yeast Prp17 may indicate an additional role in cell cycle progression for mammalian Cdc40.
- Applications:Suitable for use in Western Blot, Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
- Specificity:Recognizes endogenous levels of Cdc40. Species Crossreactivity: Human, mouse, rat
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to amino acids 181-230 of Human Cdc40.
- Shelf Life:1year
- Swiss Prot Number:O60508
- EU Commodity Code:30021010
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