The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response.
It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation.
This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta).
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CD74.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to full length human CD74.
Shelf Life：1year
Swiss Prot Number：P04233
EU Commodity Code：30021010
商品名：CD74 (CD 74, CD74, CD74 Antigen, CD74 Molecule, CLIP, DHLAG, Gamma Chain of class II Antigens, HG2A_HUMAN, HLA class II histocompatibility Antigen gamma Chain, HLA DR Antigens Associated invariant Chain, HLA DR gamma, HLA-DR Antigens-Associated invariant Chain, HLA-DR-gamma, HLADG, HLADR Antigens Associated invariant Chain, Ia Antigen Associated invariant Chain, Ia Antigen-Associated invariant Chain, Ia Associated invariant Chain, Ia gamma, Ii, Invariant Polypeptide of major histocompatibility Complex class II Antigen Associated, la-gamma, Major histocompatibility Complex class II invariant Chain, MHC HLA DR gamma Chain, MHC HLA-DR gamma Chain, p33, p35, Protein 41,) 100ul
