CD2BP2 (CD2 (cytoplasmic tail) binding protein 2), also known as LIN1, Snu40, FWP010 or U5-52K, is a 341 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one GYF domain.
Expressed in a variety of tissues, CD2BP2 exists as a bifunctional protein that, in the nucleus, is a component of the U5 small nuclear ribonucleoprotein complex and, in the cytoplasm, binds to the tail of the CD2 antigen.
Via its multifunctional activity, CD2BP2 participates in RNA splicing and regulates CD2-triggered T-lymphocyte activation.
The gene encoding CD2BP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid PBS, 0.05% sodium azide, pH 7.2.
Specificity：Recognizes endogenous levels of CD2BP2. Species Crossreactivity: Human
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to amino acids 101-150 of Human CD2BP2.
